DR. BRENDA CRABTREE RAMÍREZ


Education:

  • 2024 – Certified STEM Mentor, British Council.
  • 2023 – Leadership Certification, IDSA Leadership Institute, USA.
  • 2013 – HIV Research Training, NIH Fogarty International Center, Mexico.
  • 2007 – Specialty in Infectious Diseases, INCMNSZ.
  • 2005 – Specialty in Internal Medicine, ABC Medical Center (American British Cowdray), Mexico City.
  • 2000 – Medical Degree, Universidad La Salle.

Academic appointments:

  • Senior Researcher D, Immuno-Infectology Clinic, Department of Infectious Diseases, INCMNSZ.
  • Member of the Governing Council of the IAS as representative for Latin America and the Caribbean.
  • Member of the Expert Panel for the IAS-USA HIV treatment and prevention guidelines.
  • Member of the Executive Committee, NEAT-ID research collaboration.
  • Associate Professor, Advanced Specialty Course in HIV/AIDS, UNAM.
  • Head Professor, Advanced Specialty Course in HIV/AIDS, UNAM.
  • Member of the National System of Researchers (SNI), Level II.

Research interests:

  • Conduct of phase II–IV clinical trials of new antiretroviral treatment molecules or strategies.
  • Management of advanced HIV disease and opportunistic infections.
  • HIV studies in Latin America and the Caribbean.
  • Observational studies on HIV and its comorbidities.

Featured projects:

  • Participation as a sub-investigator in Mexico for the Caribbean, Central America, and South America in the CCASAnet HIV epidemiology network, with experience in the leadership and management of clinical trials.
  • Coordinator of international clinical trials, site leader for collaborations with networks such as ACTG and NEAT-ID, and contributor to national and international clinical practice guidelines.
  • Participation in international collaborations such as HIV:TB, IeDEA, ICONA, Fundación Huésped, and the Kirby Institute, among others.

Awards and Distinctions:

  • 2000: Graduated with honors in the professional examination for the Medical Degree, Universidad La Salle, Mexico City.
  • 2004: Graduated with honors in the professional examination for the Specialty in Internal Medicine, ABC Medical Center.
  • 2006: Recipient of the “Alfonso Caso” Medal for highest distinction in Internal Medicine, awarded by the National Autonomous University of Mexico (UNAM).

SELECTED PUBLICATIONS

  • Rivera Villegas HO, Caro-Vega Y, Trujillo-Gamboa A, Lopez-Iñiguez Á, Sierra-Madero J, Crabtree-Ramirez B. Differences in mortality in hospitalized advanced HIV disease between treatment-naive and treatment-discontinuing individuals: a comparative retrospective study from Mexico City. Clin Infect Dis. 2025; doi: 10.1093/cid/ciaf175 [Tesis de alta especialidad en VIH/SIDA]. México: Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; 2024.
  • Clinical Characteristics and Mortality of Health-Care Workers With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Mexico City. Guerrero-Torres L, Caro-Vega Y, Crabtree-Ramírez B, Sierra-Madero JG. Clin Infect Dis. 2021 Jul 1;73(1):e199-e205. doi: 10.1093/cid/ciaa1465. PMID: 32986118 Free PMC article.
  • Sierra-Barajas, N., Caro-Vega, Y., Sierra-Madero, J. G., Benavides, R. V., López-Iñiguez, A., Mejia-Castrejon, J., Juarez-Campos, K., Silva-Casarrubias, A., & Crabtree-Ramírez, B. (2025). P-1451. Missed Opportunities for HIV Diagnosis in Mexico City: Unveiling the Gender Gap. Open Forum Infectious Diseases, 12(Suppl 1), ofae631.1623. https://doi.org/10.1093/ofid/ofae631.1623
  • Mejía-Castrejón, J., Caro-Vega, Y., Sierra-Madero, J. G., López-Iñiguez, A., & Crabtree-Ramírez, B. E. (2025). The Trend in Suicide Risk Among People with HIV Before, During, and After the COVID-19 Pandemic Lockdown. AIDS and behavior, 29(2), 664–672. https://doi.org/10.1007/s10461-024-04548-z
  • Antiretroviral therapy and Kaposi’s sarcoma trends and outcomes among adults with HIV in Latin America. Castilho JL, Kim A, Jenkins CA, Grinsztejn B, Gotuzzo E, Fink V, Padgett D, Belaunzaran-Zamudio PF, Crabtree-Ramírez B, Escuder MM, Souza RA, Tenore SB, Pimentel SR, Ikeda MLR, de Alencastro PR, Tupinanbas U, Brites C, Luz E, Netto J, Cortes CP, Grangeiro A, Shepherd BE, McGowan CC; Caribbean, Central, South America network for HIV Epidemiology (CCASAnet). J Int AIDS Soc. 2021 Jan;24(1):e25658. doi: 10.1002/jia2.25658. PMID: 33405281 Free PMC article.
  • Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico. Martínez-Gamboa A, Niembro-Ortega MD, Torres-González P, Santiago-Cruz J, Velázquez-Zavala NG, Rangel-Cordero A, Crabtree-Ramírez B, Gamboa-Domínguez A, Reyes-Gutiérrez E, Reyes-Terán G, Lozano-Fernandez VH, Ahumada-Topete VH, Martínez-Ayala P, Manríquez-Reyes M, Ramírez-Hinojosa JP, Rodríguez-Zulueta P, Hernández-León C, Ruíz-Quiñones J, Rivera-Martínez NE, Chaparro-Sánchez A, Andrade-Villanueva J, González-Hernández LA, Cruz-Martínez S, Flores-Barrientos O, Gaytán-Martínez JE, Magaña-Aquino M, Cervantes-Sánchez A, Olivas-Martínez A, Araujo-Meléndez J, Del Rocío Reyes-Montes M, Duarte-Escalante E, Frías-De León MG, Ramírez JA, Taylor ML, de León-Garduño AP, Sifuentes-Osornio J. PLoS Negl Trop Dis. 2021 Mar 8;15(3):e0009215. doi: 10.1371/journal.pntd.0009215. eCollection 2021 Mar. PMID: 33684128 Free PMC article.
  • COVID-19-associated invasive pulmonary aspergillosis in a tertiary care center in Mexico City. Vélez Pintado M, Camiro-Zúñiga A, Aguilar Soto M, Cuenca D, Mercado M, Crabtree-Ramirez B; ARMII study gruop. Med Mycol. 2021 Jul 14;59(8):828-833. doi: 10.1093/mmy/myab009. PMID: 33724423 Free PMC article.
  • Estimated life expectancy gains with antiretroviral therapy among adults with HIV in Latin America and the Caribbean: a multisite retrospective cohort study. Smiley CL, Rebeiro PF, Cesar C, Belaunzaran-Zamudio PF, Crabtree-Ramirez B, Padgett D, Gotuzzo E, Cortes CP, Pape J, Veloso VG, McGowan CC, Castilho JL; Caribbean, Central and South America network for HIV epidemiology (CCASAnet). Lancet HIV. 2021 May;8(5):e266-e273. doi: 10.1016/S2352-3018(20)30358-1. Epub 2021 Apr 20. PMID: 33891877 Free PMC article.
  • HIV-positive patients presenting with peripheral blood cytopenias: is bone marrow assessment a priority? Rajme-Lopez S, Crabtree-Ramírez B, Acosta-Medina AA, Olivas-Martínez A, Bourlon C. Hematol Transfus Cell Ther. 2021 May 11:S2531-1379(21)00049-3. doi: 10.1016/j.htct.2021.02.008. Online ahead of print. PMID: 34312113 Free article.
  • Higher Veterans Aging Cohort Study 2.0 Index Score Predicts Functional Decline Among Older Adults Living with HIV. Hernández-Favela CG, Hernández-Ruiz VA, Bello-Chavolla OY, Crabtree-Ramírez B, Sierra-Madero J, Amieva H, Erlandson KM, Avila-Funes JA. AIDS Res Hum Retroviruses. 2021 Nov;37(11):878-883. doi: 10.1089/AID.2020.0295. Epub 2021 Sep 23. PMID: 34465139
  • Gandhi RT, Landovitz RJ, Sax PE, Smith DM, Springer SA, Günthard HF, Thompson MA, Bedimo RJ, Benson CA, Buchbinder SP, Crabtree-Ramirez BE, del Rio C, Eaton EF, Eron JJ Jr, Hoy JF, Lehmann C, Molina JM, Jacobsen DM, Saag MS. Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel. JAMA. 2025;333(7):609-628. doi:10.1001/jama.2024.24543