DR.SANTIAGO ÁVILA RÍOS


Education:

  • 2009 – Doctorate in Biomedical Sciences, UNAM
  • 2002 – Master in Molecular Medical Microbiology, University of Nottingham.
  • 2000 – Pharmaceutical Chemist Biologist, UNAM.

Academic appointments:

  • Assistant Professor, Department of medicine, Queen’s University.
  • Head of the Center for Research in Infectious Diseases (CIENI) of the National Institute of Respiratory Diseases (INER).
  • National System of Researchers, Level II.
  • Researcher affiliated with CISIDAT.

Research interests: 

  • Molecular epidemiology and HIV transmission networks in Mexico and Central America.
  • Surveillance of transmitted resistance to antiretroviral drugs in Latin America.
  • HLA-associated evolution of circulating HIV in the Mesoamerican region.

Education:

  • Coordinates the participation of CIENI / INER as the WHO Regional Reference Laboratory for the Technical Cooperation Network for HIV Drug Resistance for Latin America and the Caribbean.
  • He directly coordinates the CIENI / INER Molecular Biology Laboratory, mainly focused on Sanger and next-generation sequencing.

SELECTED PUBLICATIONS

  • Longitudinal variation in human immunodeficiency virus long terminal repeat methylation in individuals on suppressive antiretroviral therapy. Cortés-Rubio CN, Salgado-Montes de Oca G, Prado-Galbarro FJ, Matías-Florentino M, Murakami-Ogasawara A, Kuri-Cervantes L, Carranco-Arenas AP, Ormsby CE, Cortés-Rubio IK, Reyes-Terán G, Ávila-Ríos S. Clin Epigenetics. 2019 Sep 13;11(1):134.
  • Clinical and evolutionary consequences of HIV adaptation to HLA: implications for vaccine and cure. Avila-Rios S, Carlson JM, John M, Mallal S, Brumme ZL. Curr Opin HIV AIDS. 2019 May;14(3):194-204.
  • HIV-1 drug resistance before initiation or re-initiation of first-line ART in eight regions of Mexico: a sub-nationally representative survey. Ávila-Ríos S, García-Morales C, Valenzuela-Lara M, Chaillon A, Tapia-Trejo D, Pérez-García M, López-Sánchez DM, Maza-Sánchez L, Del Arenal-Sánchez SJ, Paz-Juárez HE, Quiroz-Morales VS, Mehta SR, Smith DM, León-Juárez EA, Magis-Rodríguez C, Reyes-Terán G; HIVDR MexNet Group . J Antimicrob Chemother. 2019 Apr 1;74(4):1044-1055.
  • Bioinformatic data processing pipelines in support of next-generation sequencing-based HIV drug resistance testing: the Winnipeg Consensus. Ji H, Enns E, Brumme CJ, Parkin N, Howison M, Lee ER, Capina R, Marinier E, Avila-Rios S, Sandstrom P, Van Domselaar G, Harrigan R, Paredes R, Kantor R, Noguera-Julian M. J Int AIDS Soc. 2018 Oct;21(10):e25193.
  • Evolutionary history and spatiotemporal dynamics of the HIV-1 subtype B epidemic in Guatemala. Mendoza Y, García-Morales C, Bello G, Garrido-Rodríguez D, Tapia-Trejo D, Pascale JM, Girón-Callejas AC, Mendizábal-Burastero R, Escobar-Urias IY, García-González BL, Navas-Castillo JS, Quintana-Galindo MC, Pinzón-Meza R, Mejía-Villatoro CR, Avila-Ríos S, Reyes-Terán G. PLoS One. 2018 Sep 13;13(9).
  • Novel HLA class I associations with HIV-1 control in a unique genetically admixed population. Valenzuela-Ponce H, Alva-Hernández S, Garrido-Rodríguez D, Soto-Nava M, García-Téllez T, Escamilla-Gómez T, García-Morales C, Quiroz-Morales VS, Tapia-Trejo D, Del Arenal-Sánchez S, Prado-Galbarro FJ, Hernández-Juan R, Rodríguez-Aguirre E, Murakami-Ogasawara A, Mejía-Villatoro C, Escobar-Urias IY, Pinzón-Meza R, Pascale JM, Zaldivar Y, Porras-Cortés G, Quant-Durán C, Lorenzana I, Meza RI, Palou EY, Manzanero M, Cedillos RA, Aláez C, Brockman MA, Harrigan PR, Brumme CJ, Brumme ZL, Ávila-Ríos S, Reyes-Terán G; Mesoamerican HIV Project Group. Sci Rep. 2018 Apr 17;8(1):6111.
  • HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis. Gupta RK, Gregson J, Parkin N, Haile-Selassie H, Tanuri A, Andrade Forero L, Kaleebu P, Watera C, Aghokeng A, Mutenda N, Dzangare J, Hone S, Hang ZZ, Garcia J, Garcia Z, Marchorro P, Beteta E, Giron A, Hamers R, Inzaule S, Frenkel LM, Chung MH, de Oliveira T, Pillay D, Naidoo K, Kharsany A, Kugathasan R, Cutino T, Hunt G, Avila Rios S, Doherty M, Jordan MR, Bertagnolio S. Lancet Infect Dis. 2018 Mar;18(3):346-355.
  • Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. Adland E, Hill M, Lavandier N, Csala A, Edwards A, Chen F, Radkowski M, Kowalska JD, Paraskevis D, Hatzakis A, Valenzuela-Ponce H, Pfafferott K, Williams I, Pellegrino P, Borrow P, Mori M, Rockstroh J, Prado JG, Mothe B, Dalmau J, Martinez-Picado J, Tudor-Williams G, Frater J, Stryhn A, Buus S, Teran GR, Mallal S, John M, Buchbinder S, Kirk G, Martin J, Michael N, Fellay J, Deeks S, Walker B, Avila-Rios S, Cole D, Brander C, Carrington M, Goulder P. J Virol. 2018 Jan 30;92(4).
  • Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico. Soto-Nava M, Avila-Ríos S, Valenzuela-Ponce H, García-Morales C, Carlson JM, Tapia-Trejo D, Garrido-Rodriguez D, Alva-Hernández SN, García-Tellez TA, Murakami-Ogasawara A; International HIV Adaptation Collaborative, Mallal SA, John M, Brockman MA, Brumme CJ, Brumme ZL, Reyes-Teran G; HIV MexNet Group. J Virol. 2018 Jan 2;92(2).
  • HIV pretreatment drug resistance trends in three geographic areas of Mexico. García-Morales C, Tapia-Trejo D, Quiroz-Morales VS, Navarro-Álvarez S, Barrera-Arellano CA, Casillas-Rodríguez J, Romero-Mora KA, Gómez-Palacio-Schjetnan M, Murakami-Ogasawara A, Ávila-Ríos S, Reyes-Terán G; HIVDR MexNet Group.